Abstract: Objective: To evaluate the impact of continuity of care on delivery outcomes in pregnant women diagnosed with gestational diabetes mellitus (GDM). Methods: This retrospective controlled study was conducted at a tertiary general hospital in Hubei Province, China. The control group consisted of 60 GDM patients who received standard prenatal care between September 2020 and September 2021. The intervention group included 200 GDM patients who received continuity of care between October 2021 and June 2023. The continuity of care model encompassed health education, dietary and exercise... [Read More]

Abstract: Background: Gestational diabetes mellitus (GDM) increases the risk of adverse neonatal outcomes, including preterm birth, macrosomia, neonatal hypoglycemia, and admission to the neonatal intensive care unit (NICU). While continuity of care has been shown to improve maternal health, its independent impact on neonatal outcomes remains insufficiently evaluated. Methods: A retrospective controlled study was conducted on 260 pregnant women with GDM treated at a tertiary hospital in Hubei Province, China (September 2020–June 2023). Participants were assigned to a control group receiving... [Read More]

Abstract: Orthopedic injuries are common clinical conditions encompassing fractures, dislocations, soft tissue injuries, and bone diseases, which severely impact patients' limb function and quality of life. Integrated Traditional Chinese and Western Medicine (TCWM) in the treatment of bone injuries, with its unique advantages of "combining syndrome differentiation with disease diagnosis, addressing both local and systemic aspects, and emphasizing both symptomatic and root cause treatment," has achieved significant clinical efficacy. This paper systematically reviews the theoretical basis and... [Read More]

Abstract: Advanced-age parturients (maternal age≥35years at delivery) have become a key population for maternal and infant safety protection due to age-related physiological decline and high incidence of pregnancy complications (e.g., pregnancy-induced hypertension, gestational diabetes mellitus). With the global trend of delayed childbearing and the implementation of China’s three-child policy, the number of advanced-age parturients has continued to rise. The traditional physician-led single midwifery model can no longer meet their individualized care needs. This article systematically reviews the... [Read More]

Abstract: Breast cancer is a common malignant tumor among women worldwide, with the HR+/HER2- subtype (Luminal type) accounting for 60%-70% of all cases. Endocrine therapy has long been the standard treatment for this subtype; however, 30% of patients exhibit primary resistance, and most initial responders develop acquired resistance after treatment, resulting in a significant disease burden. Dysregulation of the cell cycle is a key mechanism underlying endocrine resistance in this subtype. Cyclin-dependent kinases 4/6 (CDK4/6) form a complex with cyclin D, which phosphorylates the retinoblastoma... [Read More]

Abstract: Background: The conjunctiva serves as a frontline mucosal and immunologic barrier, rendering it highly susceptible to infectious, allergic, and immune-mediated insults. Conjunctivitis remains the most common ocular surface disease globally, yet its clinical management is often challenged by diagnostic ambiguity, empirical treatments, and evolving pathogen resistance. Objective: This review synthesizes recent advancements in the pharmacological management of conjunctivitis, with a focus on aligning therapeutic strategies to distinct etiologic subtypes: bacterial, viral, and allergic.... [Read More]